GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Phase II Amino Acid Conjugation Metabolism of Herbicides or Xenobiotics in Plants passel Glutathione transporter as a target for brain drug delivery Medicinal Chemistry Research Springer Nature Link PPT Drug metabolism PowerPoint Presentation, free download ID:2312754 Glutathione catalysis and the reaction mechanisms of glutathione dependent enzymes ScienceDirect
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glutathione conjugation reaction 16 Phase II reactions Conjugation with GSH paracetamol