Glucose 6 phosphate dehydrogenase (G6PD) deficiency Pathology of G6PD deficiency Pathology Made Simple In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione G6PD Deficiency Hematology Medbullets Step 1 PPT) Biochemistry of Hematology
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