De novo synaptogenesis induced by GABA in the developing mouse cortex Max Planck Neuroscience Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted A Single Cell Perspective on Remapping Human Adult Neurogenesis and Its Clinical Implications Dihexa Peptide Therapy Memory & Cognition Beverly Hills Synaptogenesis (Chapter 22) Textbook of Neural Repair and Rehabilitation