Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial ScienceDirect Novo Nordisk's CagriSema trial deals blow in obesity drug battle with Eli Lilly Reuters Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Novo Nordisk flags Cagrilintide promise in hunt for next obesity drug Cagrilintide and semaglutide together drive record weight loss in global trial